The University of Tokyo · Graduate School of Agricultural and Life Sciences / Faculty of Agriculture

Research keywords多剤排出ポンプ・ウイルス粒子構造・イネ萎縮ウイルス・タンパク質構造解析・食品由来抗菌物質

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• 【立体構造から読み解く多剤耐性のメカニズム】緑膿菌由来の2つの膜を貫く巨大な排出ポンプMexAB-OprMの構造
• African swine fever virus protein pB602L is a unique molecular chaperone promoting the folding of the major capsid protein p72 and the polyprotein processing protease pS273R
• Cryo-EM structures of a MexB–MexY chimeric efflux pump reveal that large open clefts are intrinsic to the MexY porter domain
• Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.

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