The University of Tokyo · Institute for Quantitative Biosciences · 助教

Research keywordsmedical genomics・ribosomal DNA variation・craniofacial syndrome genetics・single cell transcriptomics・cell proliferation networks・copy number variation disorders・growth retardation syndromes

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• Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor
• Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity.
• Cell cycle-dependent gene networks for cell proliferation activated by nuclear CK2α complexes.
• Mosaic ratio quantification of isochromosome 12p in Pallister–Killian syndrome using droplet digital PCR

• PAR化修飾によるクロマチン高次構造制御・遺伝子転写調節機構の包括的解析
• ポリＡＤＰリボシル化によるクロマチン構造制御の包括的理解と分子メカニズム解析
• コヒーシンによる転写伸長反応制御の実態解明に向けて
• TORC1新規in vitroアッセイ系を用いたアミノ酸感知と活性制御機構の解析

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