The University of Tokyo · Graduate School of Medical Sciences / Faculty of Medicine · 教授

Research keywords標的遺伝子置換・Cre・G11α・ES細胞・BAC

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• Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant
• Cdc42 is crucial for facial and palatal formation during craniofacial development
• Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin
• Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice

• 包括型脳科学研究推進支援ネットワーク
• mGluR1トランスジェニックマウスを用いた神経可塑性の研究
• 多発性嚢胞腎(ADPKD)疾患モデルの作成と遺伝子治療
• p53点突然変異マウス作成によるがん治療モデルの開発

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