Gifu　University　of　Medical　Science · Department of Pharmacy / Faculty of Pharmaceutical Sciences · 教授

Research keywords重金属・メタロチオネイン・多環芳香族炭化水素・転写調節・エピジェネティクス・DOHaD・神経変性疾患

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• Stem Cells From Human Exfoliated Deciduous Teeth-Conditioned Medium (SHED-CM) is a Promising Treatment for Amyotrophic Lateral Sclerosis.
• SLC20A2-Associated Idiopathic Basal Ganglia Calcification-Related Recurrent Psychosis Response to Low-Dose Antipsychotics: A Case Report and Literature Review.
• Methylmercury causes epigenetic suppression of the tyrosine hydroxylase gene in an in vitro neuronal differentiation model.
• Vacuolar Protein-Sorting Proteins Are Reduced Even Before Cognitive Decline in a Mouse Model of Alzheimer’s Disease

• MTF1の神経発生におけるエピゲノムプログラミングと神経変性疾患との関連の解明
• 神経分化影響を引き起こす低濃度メチル水銀曝露の標的エピゲノム分子の探索
• 新規PDGFRB標的の特発性基底核石灰化症に対する薬効評価
• 多機能低分子タンパクMT3を基盤としたアルツハイマー型認知症の新規治療シーズの探索

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