Gifu Pharmaceutical University · Laboratory of Biomimetics · 講師

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• RS9, a novel Nrf2 activator, attenuates light-induced death of cells of photoreceptor cells and Müller glia cells.
• Human iPSC–liver organoid transplantation reduces fibrosis through immunomodulation
• Placenta-derived factors contribute to human iPSC-liver organoid growth.
• Age-dependent induction of ER stress in retinal pigment epithelium impairs phagocytosis via ADAM17-dependent MERTK shedding

• 固形臓器の人為的創出に向けた革新的なヒトiPS細胞オルガノイド灌流培養系の構築
• 生体内環境を再現したヒト臓器発生システムの開発
• iPS細胞由来肝芽移植によるカニクイザル肝硬変治療法の開発
• 疾患モデル構築に向けたヒト血管の開発

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