Kyushu　University　of　Health　And　Welfare · Department of Pharmacy

Research keywordsrho kinase inhibition・vascular contraction・microglial cell death・prostaglandin E2・cyclooxygenase 2・RANTES signaling・mesenteric vasculature

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• Prostaglandin E2 potentiates interferon-γ-induced nitric oxide production in cultured rat microglia.
• Relationship between serotonin and vascular dysfunction and the impact of 5-HT2A receptor blockade by sarpogrelate on vascular function in diabetes mellitus.
• Naloxone selectively inhibits vasoconstriction caused by phenylephrine but not endogenous noradrenaline in the rat mesenteric vasculature.
• Prostaglandin E2 reduces amyloid beta-induced phagocytosis in cultured rat microglia.

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