University　of　Occupational　and　Environmental　Health,　Japan · Department of Biochemistry

Research keywordsYAP1・Cell・biology・Adipose・tissue

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• MOB1 deletion in murine mature adipocytes ameliorates obesity and diabetes.2025 · Proceedings of the National Academy of Sciences of the United States of America 122(17) e2424741122 2025年4月29日
• A highly sensitive reporter system to monitor endogenous YAP1/TAZ activity and its application in various human cells.2024 · Cancer science 115(10) 3370-3383 2024年10月
• N-(3,4-dimethoxyphenethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine inhibits bladder cancer progression by suppressing YAP1/TAZ.2022 · Genes to cells : devoted to molecular & cellular mechanisms 27(10) 602-612 2022年10月
• Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation.2021 · Cancer science 112(10) 4303-4316 2021年10月

• β-カテニンを活性化するヒトIRAK1特異的モチーフの役割と病態との関連2024
• 炎症性サイトカインIL-1を起点とする新規シグナル軸の解明と線維化・がんとの関連2021
• Hippo経路エフェクターYAP/TAZの方向性を規定するシグナルの検索と解析2018
• Hippo経路制御因子および破綻シグナルの検索2015

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