The University of Shiga Prefecture · Faculty of Human Nursing · 教授

Research keywordsovarian cancer screening・leg edema in pregnancy・ultrasonography・cervical cancer prevention・gynecologic oncology・lymphedema・borderline ovarian tumors

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• The effect of wearing elastic compression stockings on leg edema in pregnant women in late pregnancy as determined by measuring the deep venous velocity and flow.2025 · 担当区分： 責任著者 記述言語： 英語 掲載種別： 学位論文（博士） 出版者・発行元： MDPI 参加形態： 共同（主担当） Background: The present study evaluated the objective effectiveness of wearing compression stockings during late pregnancy on leg edema by measuring changes in venous velocity and blood flow. Methods: Using Doppler ultrasonography, we calculated the popliteal venous velocity and blood flow and compared them in the following four groups: (1) 13 non-pregnant women (26 legs) without leg edema, (2) 23 pregnant women (46 legs) in late pregnancy without leg edema, (3) 22 pregnant women (44 legs) in late pregnancy with leg edema who were followed up without treatment, and (4) 21 pregnant women (42 legs) in late pregnancy with leg edema who wore elastic compression stockings for 1 week. Results: Both the average velocity and blood flow of the popliteal vein of pregnant women’s legs in late pregnancy were significantly lower than those in non-pregnant women (6.32 ± 0.28 cm/s vs. 9.14 ± 0.37 cm/s; 118.48 ± 8.83 mL/min vs. 177.73 ± 11.74 mL/min, p < 0.0001, respectively). Furthermore, both the average venous velocity and blood flow in edematous legs in late pregnancy were significantly lower than those in non-edematous legs (5.32 ± 0.93 cm/s vs. 6.32 ± 0.28 cm/s; 82.68 ± 35.90 mL/min vs. 118.48 ± 8.83 mL/min, p < 0.0001, respectively). Finally, both the average venous velocity and blood flow were significantly higher in edematous legs in late pregnancy after wearing stockings than without treatment (7.69 ± 0.17 cm/s vs. 5.36 ± 0.17 cm/s; 143.22 ± 48.74 mL/min vs. 97.03 ± 40.07 mL/min, p < 0.0001, respectively). Conclusions: The wearing of elastic compression stockings by women with edematous legs in late pregnancy significantly increases the deep venous velocity and flow. Thus, it is possible to prevent deep vein thrombosis in this population. DOI： https://doi.org/10.3390/healthcare13030214
• A histogram analysis of the pixel grayscale (luminous intensity) of B-mode ultrasound images of the subcutaneous layer predicts the grade of leg edema in pregnant women.2023 · 担当区分： 責任著者 記述言語： 英語 掲載種別： 研究論文（学術雑誌） DOI： https://doi.org/10.3390/healthcare11091328 その他リンク： https://www.mdpi.com/2227-9032/11/9/1328
• Ovarian serous borderline tumors with recurrent or extraovarian lesions: a Japanese, retrospective, multi-institutional, population-based study.2023 · 記述言語： 英語 掲載種別： 研究論文（学術雑誌） DOI： 10.1007/s10147-023-02393-z
• Basic study for the quantitative diagnosis of edema focusing on ultrasound propagation time waveform information.2022 · 記述言語： 英語 掲載種別： 研究論文（学術雑誌） 参加形態： 共同（副担当） DOI： 10.17140/WHOJ-8-147

• 臨床疾病論G2024 · 2024年4月 - 2025年3月 機関名： 京都大学
• International Journal of Environmental Research and Public Health (PubMed 掲載誌): Editor2020 · 2020年3月 - 現在
• 子宮頸癌の予防2019 · 2019年7月 - 現在
• Medicina （PubMed 掲載誌）：Editor2019 · 2019年10月 - 現在

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