Aoyama Gakuin University · Faculty of Science and Engineering · 助教

Research keywordsraman spectroscopy・oligodeoxynucleotides・hyperpolarized magnetic resonance・synthetic biomarkers・multiplex biomolecular analysis・chemical probe design

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• The pH-Dependent Raman Signal Enhancement of an Alkyne-tagged Hoechst Molecule that Binds with Oligodeoxynucleotides on Gold Nanoparticles
• Evaluation of enzymatic and magnetic properties of γ-glutamyl-[1-13C]glycine and its deuteration toward longer retention of the hyperpolarized state
• Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection
• Hoechst‐modification on oligodeoxynucleotides for efficient transport to the cell nucleus and gene regulation

• 低酸素セラノスティクスを実現する創薬研究
• 解析対象酵素のがん組織における活性評価を実現する血中分子マーカーの開発
• DNAバーコーディングを活用した代謝物の超高感度定量
• 個体応用を指向した新規レポータータンパク質システムの創製

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