Yamagata University · Faculty of Medicine

Research keywordsglioma stem cells・MKK4・7 inhibition・HDAC1 HDAC2 inhibition・meningioma・senolytic therapy・ovarian clear cell carcinoma

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• Targeting Bcl-xL with Navitoclax Effectively Eliminates Senescent Tumor Cells That Appear Following CEP-1347-Induced Differentiation of Glioma Stem Cells，International Journal of Molecular Sciences，26(14) 6984，2025年07月2025 · Senri Takenouchi , Yasufumi Ito , Kazuki Nakamura , Yurika Nakagawa-Saito , Yuta Mitobe , Keita Togashi , Shuhei Suzuki , Asuka Sugai , Yukihiko Sonoda , Chifumi Kitanaka , Masashi Okada
• Efficient Inhibition of FOXM1 Expression and Viability of High-grade Meningioma Cells by Domatinostat-mediated Dual Targeting of HDAC1 and HDAC2，Anticancer Research，45(11) 4853-4868，2025年11月2025 · Kazuki Nakamura , Yasufumi Ito , Yurika Nakagawa-Saito , Senri Takenouchi , Shuhei Suzuki , Keita Togashi , Asuka Sugai , Yuta Mitobe 1, Yukihiko Sonoda , Chifumi Kitanaka , Masashi Okada
• HDAC Class I Inhibitor Domatinostat Induces Apoptosis Preferentially in Glioma Stem Cells Through p53-Dependent and -Independent Activation of BAX Expression，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，26(16) ，2025年08月2025 · Nakagawa-Saito, Y; Ito, Y; Nakamura, K; Mitobe, Y; Togashi, K; Suzuki, S; Takenouchi, S; Sugai, A; Sonoda, Y; Kitanaka, C; Okada, M
• Extracranial Thrombosed Vertebral Aneurysm Associated Neurofibromatosis Type1 Treated by Neuroendovascular Coil Embolization，Clinical Case Reports，13(1) e70066，2025年01月2025 · Kenshi Sano , Atsushi Kuge , Rei Kondo , Tetsu Yamaki , Kazuki Nakamura , Shinjiro Saito , Yukihiko Sonoda

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