Yamaguchi University · Research Institute for Cell Design Medical Science · 教授

Research keywordsネフロン・再生医学・尿細管・発生生物学・糸球体・腎臓前駆細胞・腎臓発生・ES細胞

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• Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: Molecular mechanisms and structure-activity relationship
• Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma.
• PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids
• Expanding nephron progenitors in vitro: a step toward regenerative medicine in nephrology.

• ヒトiPS細胞からつくった腎臓の元細胞を増やすことに成功 ～腎臓の再生医療に向け前進～
• ヒト腎臓ネフロン前駆細胞の多能性維持機構解明による増幅培養法の確立
• 腎臓ネフロン前駆細胞の維持機構解明による自己複製法の確立
• ヒトiPS細胞で小児腎臓病を再現～病態解明と治療に向けた大きな前進～

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