Yamaguchi University · Graduate School of Medical Sciences

Research keywords転写・分子生物学・熱ショックタンパク質・医化学・生化学・熱ショック転写因子・がん・プロテオスタシス

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• HSF1/HSP25 system protects mitochondria function from heat stress and assists steroidogenesis in MA-10 Leydig cells2025 · Molecular and Cellular Endocrinology
• HSF1 is required for cellular adaptation to daily temperature fluctuations2024 · Scientific Reports
• The Mediator subunit MED12 promotes formation of HSF1 condensates on heat shock response element arrays in heat-shocked cells.2023 · FEBS letters
• Regulation of HSF1 transcriptional complexes under proteotoxic stress: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates.2023 · BioEssays : news and reviews in molecular, cellular and developmental biology

• がんにおけるHSF1複合体を介したエピゲノム制御機構の解明2023 · 科学研究費助成事業
• HSF1複合体によるエピジェネティックな遺伝子発現制御2019
• HSF1複合体によるエピジェネティックな遺伝子発現制御機構の解明2019 · 科学研究費助成事業 基盤研究(C)
• HSF1による新規転写調節機構を介したプロテオスタシス維持機構の解明2018 · 科学研究費助成事業 基盤研究(B)

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