Yasuda Women's University · Department of Pharmacy · 教授

Research keywords医薬化学・創薬化学・創薬・有機化学・有機合成・酵素阻害剤・細胞周期・KSP阻害・IDO阻害・PARG阻害

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• Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation
• Discovery of Carbono(di)thioates as Indoleamine 2,3-Dioxygenase 1 Inhibitors.
• Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives
• Eperisone Analogs, Rescuers ofMiaBDefects As a Prokaryotic Homologue ofCDKAL1, Suppress Blood Glucose Elevation in Rats

• LSD阻害剤の創製：LSD1阻害剤の創薬展開およびLSD2機能解明の基盤構築
• 革新的抗がん剤の創製を目指したIDO阻害剤の医薬化学研究
• IDO阻害剤の実践的創薬展開による革新的抗がん剤創製の基盤構築
• Indoleamine 2,3-dioxygenase（IDO）阻害剤の創製による『がん免疫寛容』機構解明と画期的がん治療体系確立の基盤構築

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