Yasuda Women's University · Department of Pharmacy · 教授

Research keywordsケミカルバイオロジー・バイオコンジュゲート・バイオテクノロジー・核酸・核酸医薬・生物有機化学・RNAi・siRNA・アンチセンス

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• Heat shock-induced heme oxygenase-1 expression in a mouse hepatoma cell line is dependent on HSF1 and modified by NRF2 and BACH1.
• Agr2 Mediates Paracrine Effects on Stromal Fibroblasts That Promote Invasion by Gastric Signet-Ring Carcinoma Cells
• Synthesis and Biolgical Activity of DNA-NLS Peptide Conjugate.
• Lipid-siRNA Conjugates Targeting High PD-L1 Expression as Potential Novel Immune Checkpoint Inhibitors

• Potent Gene Silencing in a Liver-Metastatic Tumor Mouse Model Using Lipid Conjugated siRNAs.
• 医薬応用に向けたジヒドロピリミジン誘導体のレチノイドとしての機能開発
• In vivoにおける脂肪酸修飾型2本鎖RNAのRNA干渉効果についての研究
• In vivoにおける脂肪酸修飾型2本鎖RNAのRNA干渉効果についての研究

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