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Home›Data center›Researcher database›Kojima Chojiro

教授

Kojima Chojiro

児嶋 長次郎

Yokohama National University · Faculty of Science and Engineering, Division of Chemistry and Life Sciences

Affiliation
Yokohama National University · Faculty of Science and Engineering, Division of Chemistry and Life Sciences
Research keywords
Biochemistry, Combinatorial, Drug, Fluorine-19, NMR, Nuclear, Small, Transcription
Research fields
Biophysics, Structural biochemistry, Chemical biology, Medicine, 医学一般, 基礎生物科学, Functional biochemistry, Living organism molecular science, Living organism molecular science, Biology, Biological science, Biological Sciences, Laboratory medicine, Integrated Science and Innovative Science, New Multidisciplinary Fields, Complex systems
Funded projects
34 grants · latest 2024

Recent work

  • NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA（2025）
  • An NLR paralog Pit2 generated from tandem duplication of Pit1 fine-tunes Pit1 localization and function（2024）
  • Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening（2022）
  • Cooperative regulation of PBI1 and MAPKs controls WRKY45 transcription factor in rice immunity（2022）
  • 19F chemical library and 19F-NMR for a weakly bound complex structure（2022）

Funded projects

  • 低分子化合物ライブラリーを用いたフッ素NMRスクリーニング
  • フロリゲン（花成ホルモン）の分子機能解明と植物改良への展開
  • タンパク質複合体の立体構造と機械学習によるゲノムに潜む免疫ペプチドの網羅的探索
  • ＲＮＡ分子の細胞内構造プローブ法開発と細胞質スプライシング機構解析
  • 主要栄養シグナルを感知・統合するTORキナーゼ複合体ネットワーク

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