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Home›Data center›Researcher database›Nishikawa Makiya

教授

Nishikawa Makiya

西川 元也

Tokyo University of Science · Faculty of Pharmaceutical Sciences

Affiliation
Tokyo University of Science · Faculty of Pharmaceutical Sciences
Research keywords
drug delivery, dna hydrogels, albumin nanoparticles, oligonucleotide therapeutics, breast cancer, stem cell sheets
Research fields
Physical pharmacy, Applied pharmacology, Pharmacy, Chemical biology, Medicine, 医学一般, Medicine, Dentistry, and Pharmacy, Medical pharmacy, 医薬分子機能学, Boundary medicine, Clinical surgery, 応用薬理学・医療系薬学, Living organism molecular science, Biological Sciences, Biological pharmacy, Ophthalmology, Integrated Disciplines, Complex systems
Funded projects
51 grants · latest 2024

Recent work

  • Induction of sustained antibody responses by subcutaneous administration of immunostimulatory Takumi-shaped CpG DNA hydrogel loaded with Japanese cedar pollen antigen Cryj1 in mice（2025）
  • Pharmacokinetics and protein binding of cholesterol-conjugated heteroduplex oligonucleotide（2025）
  • Biocompatible DNA hydrogel composed of minimized Takumi-shaped DNA nanostructure exhibits sustained retention after in vivo administration（2025）
  • DNAハイドロゲルを利用した核酸デリバリーシステム（2025）
  • Folate-targeted pH-sensitive albumin nanoparticles loaded with Baicalin enhance tamoxifen efficacy and overcome drug resistance in estrogen receptor alpha-positive breast cancer（2025）

Funded projects

  • がん増殖・転移におけるバイオイメージングとターゲティング型DDS開
  • 化学修飾によるプラスミドDNAのナノ粒子化とDDS
  • 筋ジストロフィーに対する根本的治療を実現するための技術集約的研究
  • Study on Dosage Form Design for Gene Therapy
  • 動態制御機能を賦与したキメラタンパク質発現ベクターによる新規遺伝子治療戦略

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