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Home›Data center›Researcher database›Kakimi Kazuhiro

教授

Kakimi Kazuhiro

垣見 和宏

Kindai University · Faculty of Medicine

Affiliation
Kindai University · Faculty of Medicine
Research keywords
immuntoherapy, 癌免疫, cancer immunology, 免疫細胞治療, Immunology, Cancer, research, Immune
Research fields
Radiation science, Digestive surgery, Biofunction/Bioprocess, Oncology, Process/Chemical engineering, Process engineering, Biomedical engineering, Immunology, Clinical internal medicine, Medicine, Dentistry, and Pharmacy, Biomedical engineering/Biological material science, Respiratory surgery, Basic medicine, Clinical surgery, Engineering, Surgery of the organs maintaining homeostasis and related fields, Urology, Gastroenterology, Science and Engineering, Biological Sciences
Funded projects
62 grants · latest 2025

Recent work

  • Mathematical modeling of immune counter-regulation predicts efficacy of fractionated CD8+ T cell dosing strategies.（2026）
  • Neoantigen-mRNA-LNP Vaccine Induces Potent Anti-Tumor CD8+ T cell responses in the tumor（2025）
  • Adjuvant combination therapy with gemcitabine and autologous γδ T-cell transfer in patients with curatively resected pancreatic cancer.
  • Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration
  • Advantage of dendritic cells for the therapeutic cancer vaccine

Funded projects

  • 腎癌を対象としたインターフェロン併用樹状細胞療法の臨床応用に関する研究
  • 免疫チェックポイント阻害剤抵抗性肺がんに対するネオアンチゲンワクチン治療の開発
  • 転移性肺腫瘍における癌免疫微小環境の時間空間的多様性の解明
  • T細胞受容体遺伝子導入T細胞を用いたNeoantigen 解析システム
  • リバースＴＲ（橋渡し研究）としての腫瘍内免疫応答の解析とバイオマーカーの検索

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